2025-03-26 17:52:35
3月26日上午,中南大学湘雅三医院血液内科干细胞采集室内,一场特殊的生命传递正在进行——年仅4岁半的同卵双胞胎姐妹,在医护人员的陪同下,一边拿着画板坐在床上画画,一边通过外周血干细胞分离机为身患急性白血病的母亲捐献造血干细胞。这是该院首次采用两名低龄双胞胎同步捐献外周血干细胞救治成人患者的案例。
“儿童供者体重通常需达到受者体重的三分之一以上,但是孩子显然不达标,于是我们想到了用同一基因型的姐妹俩共同采集。”主治医生中南大学湘雅三医院血液内科李颖副教授介绍,单靠一个孩子的干细胞量不能满足成人移植需求,而分次采集又可能延误移植时机。
经多学科专家反复论证,团队最终决定采用“双供者联合采集”的方案:同步动员两名双胞胎的造血干细胞,既不让孩子重复采集和穿刺的痛苦,又能及时的采够支撑起母亲生命的造血干细胞。
令人动容的是,平时打疫苗也会哭的孩子,因为知道自己是来“救妈妈”的,在进行干细胞采集时一声不吭,态度特别配合。当被问及打针痛不痛时,孩子轻轻摇头,“我们一起保护妈妈”。(来源:新湖南,视频:向希)
On the morning of March 26, a special life transfer was taking place in the stem cell collection room of the Hematology Department of Xiangya Third Hospital, Central South University. a pair of four and a half years old identical twin sisters sat on a hospital bed, drawing on their sketchpads while donating peripheral hematopoietic stem cells to save their mother battling acute leukemia. This marks the hospital’s first case of two young twins donating stem cells simultaneously to save an adult patient.
Typically, a child donor’s weight should be at least one-third of the recipient’s, but these girls didn’t meet that requirement. So, we decided to collect stem cells from both genetically identical sisters," explained Dr. Li Ying, associate professor at the hospital’s Hematology Department. A single child’s stem cell volume wouldn’t suffice for an adult transplant, while sequential collections could delay treatment.
After thorough discussions with multidisciplinary experts, the medical team opted for a synchronized stem cell mobilization strategy. This method ensured that both girls could donate at the same time, minimizing pain from repeated procedures while providing enough stem cells to support their mother’s recovery.
What moved everyone was how bravely the girls behaved. Though they usually cry during vaccinations, they stayed completely still during the stem cell collection, knowing they were there to "save Mommy." When asked if the needle hurt, one softly shook her head and whispered, "We're protecting Mommy together."(翻译:潘晓慧)
责编:潘晓慧
一审:潘晓慧
二审:邓望军
三审:谭登
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